Biology

This open access volume presents a novel computational framework for understanding how collections of excitable cells work. The key approach in the text is to model excitable tissue by representing the individual cells constituting the tissue. This is in stark contrast to the common approach where homogenization is used to develop models where the cells are not explicitly present. The approach allows for very detailed analysis of small collections of excitable cells, but computational challenges limit the applicability in the presence of large collections of cells.

Architects of Structural Biology is an amalgam of memoirs, biography, and intellectual history of the personalities and single-minded devotion of four scientists who are among the greatest in modern times. These three chemists and one physicist, all Nobel laureates, played a pivotal role in the creation of a new and pervasive branch of biology. This led in turn to major developments in medicine and to the treatment of diseases as a result of advances made in arguably one of the greatest centres of scientific research ever: the Laboratory of Molecular Biology in Cambridge, which they helped to establish. Their work and that of their predecessors at the Royal Institution in London reflects the broader cultural, scientific and educational strength of the UK from the early 19th century onwards. The book also illustrates the nurturing of academic life in the collegiate system, exemplified by the activities of, and cross-fertilization within, a small Cambridge college.

It was long believed that evolutionary theories received an almost universally cold reception in British natural history circles in the first half of the nineteenth century. However, a relatively recently serious doubt has been cast on this assumption. This book shows that Edinburgh in the late 1820s and early 1830s was witness to a ferment of radical new ideas on the natural world, including speculation on the origin and evolution of life, at just the time when Charles Darwin was a student in the city. Those who were students in Edinburgh at the time could have hardly avoided coming into contact with these new ideas. This book is the first major study of what was probably the most important centre or pre-Darwinian evolutionary thought in the British Isles. It sheds new light on the genesis and development of one of the most important scientific theories in the history of western thought.

Theoretical Ecology: concepts and applications continues the authoritative and established sequence of theoretical ecology books initiated by Robert M. May which helped pave the way for ecology to become a more robust theoretical science, encouraging the modern biologist to better understand the mathematics behind their theories. This latest installment builds on the legacy of its predecessors with a completely new set of contributions. Rather than placing emphasis on the historical ideas in theoretical ecology, the Editors have encouraged each contribution to: synthesize historical theoretical ideas within modern frameworks that have emerged in the last 10-20 years (e.g. bridging population interactions to whole food webs); describe novel theory that has emerged in the last 20 years from historical empirical areas (e.g. macro-ecology); and finally to cover the rapidly expanding area of theoretical ecological applications (e.g. disease theory and global change theory).

Urban Evolutionary Biology fills an important knowledge gap on wild organismal evolution in the urban environment, whilst offering a novel exploration of the fast-growing new field of evolutionary research. The growing rate of urbanization and the maturation of urban study systems worldwide means interest in the urban environment as an agent of evolutionary change is rapidly increasing.We are presently witnessing the emergence of a new field of research in evolutionary biology. Despite its rapid global expansion, the urban environment has until now been a largely neglected study site among evolutionary biologists. With its conspicuously altered ecological dynamics, it stands in stark contrast to the natural environments traditionally used as cornerstones for evolutionary ecology research.Urbanization can offer a great range of new opportunities to test for rapid evolutionary processes as a consequence of human activity, both because of replicate contexts for hypothesis testing, but also because cities are characterized by an array of easily quantifiable environmental axes of variation and thus testable agents of selection.

Nature is all around us, in the beautiful but also in the unappealing and functional, and from the awe-inspiring to the mundane. It is vital that we learn to see the agency of the natural world in all things that make our lives possible, comfortable and profitable. The Ecology of Everyday Things pulls back the veil of our familiarity on a range of 'everyday things' that surround us, and which we perhaps take too much for granted. This key into the magic world of the everyday can enable us to take better account of our common natural inheritance. Professor James Longhurst, Assistant Vice Chancellor, University of the West of England (UWE Bristol) For many people, ecosystems may be a remote concept, yet we eat, drink, breathe and interface with them in every moment of our lives. In this engaging textbook, ecosystems scientist Dr. Mark Everard considers a diversity of 'everyday things', including fascinating facts about their ecological origins: from the tea we drink, to the things we wear, read and enjoy, to the ecology of communities and space flight, and the important roles played by germs and 'unappealing creatures' such as slugs and wasps.

Written for undergraduate and graduate students with little or no mathematical background, Biostatistics for Population Health: A Primer offers current and future health professionals a clear, and accessible approach to learning the basic tools and techniques necessary to conduct biostatistical analyses and the professional confidence to critically evaluate and interpret biostatistical findings.Each unit begins with a contemporary population health issue (e.g., the opioid crisis, physical inactivity among children, diabetes) and raises questions that require the use of techniques discussed in that unit. Each technique, in turn, is illustrated with realistic, contemporary examples (e.g. vaping) to pique student interest. By the end of the unit, students are encouraged to apply the techniques to address the questions that were raised.Key Features:* Contemporary, realistic examples and straightforward approach makes material accessible to students with minimal background.*

Developing Ecological Consciousness is a unique environmental studies textbook. Rather than working through a list of environmental problems, it aims to help students become aware of the awe and wonder of our planet, understand some of the challenges facing it, and explore possibilities for action and change. This text is appropriate for courses in a variety of disciplines, including environmental studies, biology, sociology, and political science.

"The book illustrates how Darwin's theory has evolved, about the development of the biological world before Darwin, and great changes that took place with the incorporation of statistics, and after Darwin's death of genetics and mathematics. The formation of 'Modern Synthesis', protein electrophoresis, Discovery of DNA opened new avenues for the study of evolution"--

The renowned biologist Paul Nurse has spent his career revealing how living cells work. In What Is Life?, he takes up the challenge of describing what it means to be alive in a way that every reader can understand.It is a shared journey of discovery; step-by-step Nurse illuminates five great ideas that underpin biology--the Cell, the Gene, Evolution by Natural Selection, Life as Chemistry, and Life as Information. He introduces the scientists who made the most important advances, and, using his personal experiences in and out of the lab, he shares with us the challenges, the lucky breaks, and the thrilling eureka moments of discovery.Nurse writes with delight at life's richness and with a sense of the urgent role of biology in our time. To survive the challenges that face us all today--climate change, pandemic, loss of biodiversity and food security--it is vital that we all understand what life is.